Leonard R. Appleman : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (51)
Les plus populaires
Liste
- Liste
- Tableau

1

Helper T cell anergy: from biochemistry to cancer pathophysiology and therapeutics

Leonard J. Appleman, Dimitrios Tzachanis, Thomas Grader-Beck, Andre A.F.L. van Puijenbroek, Vassiliki A. Boussiotis

Journal:

Journal of Molecular Medicine

Année:

2001

Langue:

english

Fichier:

PDF, 164 KB

english, 2001

2

Broccoli-Derived Sulforaphane and Chemoprevention of Prostate Cancer: From Bench to Bedside

Amjad, Ali I., Parikh, Rahul A., Appleman, Leonard J., Hahm, Eun-Ryeong, Singh, Kamayani, Singh, Shivendra V.

Journal:

Current Pharmacology Reports

Année:

2015

Langue:

english

Fichier:

PDF, 377 KB

english, 2015

3

Clinical activity of nivolumab in patients with non-clear cell renal cell carcinoma

Koshkin, Vadim S., Barata, Pedro C., Zhang, Tian, George, Daniel J., Atkins, Michael B., Kelly, William J., Vogelzang, Nicholas J., Pal, Sumanta K., Hsu, JoAnn, Appleman, Leonard J., Ornstein, Moshe C

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2018

Langue:

english

Fichier:

PDF, 467 KB

english, 2018

4

Phase I clinical trial of bortezomib in combination with gemcitabine in patients with advanced solid tumors

David P. Ryan, Leonard J. Appleman, Thomas Lynch, Jeffrey G. Supko, Panagiotis Fidias, Jeffrey W. Clark, Mayer Fishman, Andrew X. Zhu, Peter C. Enzinger, Oscar Kashala, James Cusack Jr., Joseph P. Ede

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 114 KB

english, 2006

5

A Phase I study of bortezomib plus irinotecan in patients with advanced solid tumors

David P. Ryan, Bert H. O'Neil, Jeffrey G. Supko, Carlo M. Rocha Lima, E. Claire Dees, Leonard J. Appleman, Jeffrey Clark, Phinos Fidias, Robert Z. Orlowski, Oscar Kashala, Joseph P. Eder, James C. Cus

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 278 KB

english, 2006

6

Mouse embryo fibroblasts transformed by activated ras or dominant-negative p53 express cross-reactive tumor rejection antigens

Leonard J. Appleman, James Uyeki, Alan B. Frey

Journal:

International Journal of Cancer

Année:

1995

Langue:

english

Fichier:

PDF, 929 KB

english, 1995

7

Dominant-negative p53 can restore tumorigenicity of L-929 cells in immunocompetent mice

Leonard J. Appleman, Alan B. Frey

Journal:

International Journal of Cancer

Année:

1995

Langue:

english

Fichier:

PDF, 987 KB

english, 1995

8

T cell anergy and costimulation

Leonard J. Appleman, Vassiliki A. Boussiotis

Journal:

Immunological Reviews

Année:

2003

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2003

9

Phase I clinical trial of the farnesyltransferase inhibitor BMS-214662 administered as a weekly 24

Joseph P. Eder, David P. Ryan, Leonard Appleman, Andrew X. Zhu, Thomas Puchalski, Xiaoying He, Daryl S. Sonnichsen, Michael Cooper, John Wright, Jeffrey W. Clark, Jeffrey G. Supko

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 276 KB

english, 2006

10

A phase I open-label study evaluating the cardiovascular safety of sorafenib in patients with advanced cancer

Anthony W. Tolcher, Leonard J. Appleman, Geoffrey I. Shapiro, Alain C. Mita, Frank Cihon, Arthur Mazzu, Pavur R. Sundaresan

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 265 KB

english, 2011

11

Effect of a proton pump inhibitor on the pharmacokinetics of imatinib

Merrill J. Egorin, Dhvani D. Shah, Susan M. Christner, Mara A. Yerk, Kristin A. Komazec, Leonard R. Appleman, Robert L. Redner, Brian M. Miller, Jan H. Beumer

Journal:

British Journal of Clinical Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 525 KB

english, 2009

12

Pharmacologic Administration of Interleukin-2 : Inducing a Systemic Autophagic Syndrome?

Antonio Romo de Vivar Chavez, William Buchser, Per H. Basse, Xiaoyan Liang, Leonard J. Appleman, Jodi K. Maranchie, Herbert Zeh, Michael E. de Vera, Michael T. Lotze

Journal:

Annals of the New York Academy of Sciences

Année:

2009

Langue:

english

Fichier:

PDF, 460 KB

english, 2009

13

Tumor Antigens Encoded by Oncogenes and the Impact of Oncogenes upon the Immune Response

Leonard J. Appleman, Alan B. Frey

Journal:

Cellular Immunology

Année:

1996

Langue:

english

Fichier:

PDF, 110 KB

english, 1996

14

Phase I and pharmacokinetic study of dasatinib and cetuximab in patients with advanced solid malignancies

Athanassios Argiris, Trevor M. Feinstein, Lin Wang, Tianbing Yang, Shruti Agrawal, Leonard J. Appleman, Ronald G. Stoller, Jennifer R. Grandis, Ann Marie Egloff

Journal:

Investigational New Drugs

Année:

2012

Langue:

english

Fichier:

PDF, 460 KB

english, 2012

15

Rat Adenocarcinoma 13762 Expresses Tumor Rejection Antigens but Tumor-Bearing Animals Exhibit Tumor-Specific Immunesuppression

Alan B. Frey, Leonard J. Appleman

Journal:

Clinical Immunology and Immunopathology

Année:

1993

Fichier:

PDF, 929 KB

1993

16

Selective kinase inhibition with daily imatinib intensifies toxicity of chemotherapy in patients with solid tumours

Suzanne George, Jayesh Desai, J. Paul Eder, Judith Manola, David P. Ryan, Leonard J. Appleman, George D. Demetri

Journal:

European Journal of Cancer

Année:

2006

Langue:

english

Fichier:

PDF, 157 KB

english, 2006

17

Phase 2 trial of linifanib (ABT-869) in patients with advanced renal cell cancer after sunitinib failure

Nizar M. Tannir, Yu-Ning Wong, Christian K. Kollmannsberger, Marc S. Ernstoff, David J. Perry, Leonard J. Appleman, Edwin M. Posadas, Daniel Cho, Toni K. Choueiri, Andrew Coates, Neeraj Gupta, Rajendr

Journal:

European Journal of Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 322 KB

english, 2011

18

P-348 A phase I trial of gemcitabine followed by flavopiridol in patients with solid tumors

Goffin, John, Appleman, Leonard, Ryan, David, Fidias, Panos, Lucca, Joan, Regan, Eileen, Dimitrios Colevas, A., Eder, Joseph Paul, Supko, Jeffrey, Shapiro, Geoffrey

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 369 KB

english, 2003

19

Renal Cell Carcinoma from a Transplanted Allograft: Two Case Reports and a Review of the Literature

Wassim McHayleh, John P. Morcos, Tong Wu, Ron Shapiro, Samuel Yousem, Leonard Appleman, David M. Friedland

Journal:

Clinical Genitourinary Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 565 KB

english, 2008

20

Simple and Complex

Leng, Siyang, Nallamothu, Brahmajee K., Saint, Sanjay, Appleman, Leonard J., Bump, Gregory M.

Journal:

Boston Medical and Surgical Journal

Année:

2013

Langue:

english

Fichier:

PDF, 969 KB

english, 2013

21

Calcium carbonate does not affect imatinib pharmacokinetics in healthy volunteers

Tawbi, Hussein, Christner, Susan M., Lin, Yan, Johnson, Matthew, Mowrey, Emily T., Cherrin, Craig, Chu, Edward, Lee, James J., Puhalla, Shannon, Stoller, Ronald, Appleman, Leonard R., Miller, Brian M.

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 212 KB

english, 2014

22

Calcium carbonate does not affect nilotinib pharmacokinetics in healthy volunteers

Tawbi, Hussein A., Tran, An L., Christner, Susan M., Lin, Yan, Johnson, Matthew, Mowrey, Emily, Appleman, Leonard R., Stoller, Ronald, Miller, Brian M., Egorin, Merrill J., Beumer, Jan H.

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 380 KB

english, 2013

23

MP70-20 A PHASE 2 TRIAL OF PROSTATE SPECIFIC MEMBRANE ANTIGEN ANTIBODY DRUG CONJUGATE (PSMA ADC) IN TAXANE-TREATED METASTATIC CASTRATION-RESISTANT PROSTATE CANCER (MCRPC)

Petrylak, Daniel, Smith, David C., Appleman, Leonard J., Fleming, Mark, Hussain, Arif, Dreicer, Robert, Sartor, A. Oliver, Shore, Neil, Vogelzang, Nicholas J., Youssoufian, Hagop, Olson, William, Stam

Journal:

The Journal of Urology

Année:

2014

Langue:

english

Fichier:

PDF, 311 KB

english, 2014

24

MP23-09 INTEGRATED ANALYSIS OF METASTATIC DISEASE IN CLEAR CELL RENAL CELL CARCINOMA: A COLLABORATIVE TCGA ANALYSIS

Hakimi, A Ari, Jacobsen, Anders, Mano, Roy, Gonen, Mithat, Voss, Martin H., Reuter, Victor E., Rathmell, W Kimryn, Maranchie, Jodi K., Appleman, Leonard J., Tamboli, Pheroze, Signoretti, Sabina, Choue

Journal:

The Journal of Urology

Année:

2014

Langue:

english

Fichier:

PDF, 196 KB

english, 2014

25

Mifepristone: pharmacology and clinical impact in reproductive medicine, endocrinology and oncology

Im, Annie, Appleman, Leonard J

Journal:

Expert Opinion on Pharmacotherapy

Année:

2010

Langue:

english

Fichier:

PDF, 590 KB

english, 2010

26

Upregulation of the ATR-CHEK1 pathway in oral squamous cell carcinomas

Parikh, Rahul A., Appleman, Leonard J., Bauman, Julie E., Sankunny, Madhav, Lewis, Dale W., Vlad, Anda, Gollin, Susanne M.

Journal:

Genes, Chromosomes and Cancer

Année:

2014

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2014

27

Inhibiting Autophagy

Lotze, Michael T., Maranchie, Jodi, Appleman, Leonard

Journal:

The Cancer Journal

Année:

2013

Langue:

english

Fichier:

PDF, 212 KB

english, 2013

28

Renal Medullary Carcinoma: Case Report of an Aggressive Malignancy with Near-Complete Response to Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin Chemotherapy

Amjad, Ali Imran, Ali, Hira, Appleman, Leonard J., Maranchie, Jodi, Jackman, Stephen, Parwani, Anil, Dhir, Rajiv, Roy, Somak, Parikh, Rahul A.

Journal:

Case Reports in Oncological Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2014

29

DLK1: A Novel Target for Immunotherapeutic Remodeling of the Tumor Blood Vasculature

Chi Sabins, Nina, Taylor, Jennifer L, Fabian, Kellsye PL, Appleman, Leonard J, Maranchie, Jodi K, Stolz, Donna Beer, Storkus, Walter J

Journal:

Molecular Therapy

Année:

2013

Langue:

english

Fichier:

PDF, 2.22 MB

english, 2013

30

Induction of Immunologic Tolerance for Allogeneic Hematopoietic Cell Transplantation

Appleman, Leonard J., Tzachanis, Dimitrios, Grader-Beck, Thomas, Van Puijenbroek, Andre A. F. L., Boussiotis, Vassiliki A.

Journal:

Leukemia and Lymphoma

Année:

2002

Langue:

english

Fichier:

PDF, 917 KB

english, 2002

31

MP82-09 PROSTATE SPECIFIC MEMBRANE ANTIGEN ANTIBODY DRUG CONJUGATE (PSMA ADC) IN PATIENTS (PTS) WITH PROGRESSIVE METASTATIC CASTRATION-RESISTANT PROSTATE CANCER (MCRPC) FOLLOWING ABIRATERONE AND/OR ENZALUTAMIDE (ABI/ENZ): RESULTS FROM A PHASE 2 STUDY

Petrylak, Daniel, Vogelzang, Nicholas, Chatta, Kamal, Fleming, Mark, Smith, David, Appleman, Leonard, Hussain, Arif, Modiano, Manuel, Singh, Parminder, Tagawa, Scott, Gore, Ira, McClay, Ed, Mega, Anth

Journal:

The Journal of Urology

Année:

2015

Langue:

english

Fichier:

PDF, 336 KB

english, 2015

32

Tyrosine Kinase and Mammalian Target of Rapamycin Inhibitors in the Treatment of Advanced Renal Cell Carcinoma: Practical Clinical Implications of Pharmacologic Features

Parikh, Rahul A., Appleman, Leonard J., Beumer, Jan H., Matczak, Ewa, Chu, Edward

Journal:

Clinical Genitourinary Cancer

Année:

2016

Langue:

english

Fichier:

PDF, 463 KB

english, 2016

33

Impact of annual hospital volume of high dose interleukin-2 infusions on in-patient mortality in patients with melanoma and renal cell carcinoma

Mehta, Kathan, Appleman, Leonard, Wang, Hong, Tarhini, Ahmad, Parikh, Rahul

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 424 KB

english, 2015

34

Molecular Subtypes Improve Prognostic Value of International Metastatic Renal Cell Carcinoma Database Consortium Prognostic Model

de Velasco, Guillermo, Culhane, Aedín C., Fay, André P., Ari Hakimi, A., Voss, Martin H., Tannir, Nizar M., Tamboli, Pheroze, Appleman, Leonard J., Bellmunt, Joaquim, Kimryn Rathmell, W., Albiges, Lau

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 519 KB

english, 2017

35

Simultaneous quantitation of abiraterone, enzalutamide, N -desmethyl enzalutamide, and bicalutamide in human plasma by LC–MS/MS

Kim, Kyu-pyo, Parise, Robert A., Holleran, Julianne L., Lewis, Lionel D., Appleman, Leonard, van Erp, Nielka, Morris, Michael J., Beumer, Jan H.

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

2017

Langue:

english

Fichier:

PDF, 528 KB

english, 2017

36

ECOG-ACRIN (E4805) Randomized Phase II Study to Determine the Effect of 2 Different Doses of Aflibercept in Patients with Metastatic Renal Cell Carcinoma

Pili, Roberto, Jegede, Opeyemi, Carducci, Michael A., Manola, Judith, Groteluschen, David L., Appleman, Leonard L., Liu, Glenn, Shanks, James C., Dakhil, Shaker R., Dutcher, Janice, DiPaola, Robert S.

Journal:

Clinical Genitourinary Cancer

Année:

2017

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2017

37

Systemic therapy following metastasectomy for renal cell carcinoma: Using insights from other clinical settings to address unanswered questions

Appleman, Leonard J., Maranchie, Jodi K.

Journal:

Urologic Oncology: Seminars and Original Investigations

Année:

2017

Langue:

english

Fichier:

PDF, 250 KB

english, 2017

38

Phase I study of veliparib in combination with gemcitabine

Stoller, Ronald, Schmitz, John C., Ding, Fei, Puhalla, Shannon, Belani, Chandra P., Appleman, Leonard, Lin, Yan, Jiang, Yixing, Almokadem, Salah, Petro, Daniel, Holleran, Julianne, Kiesel, Brian F., K

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 757 KB

english, 2017

39

Radium-223 Therapy for Patients with Metastatic Castrate-Resistant Prostate Cancer: An Update on Literature with Case Presentation

Nguyen, Nghi C., Shah, Muhammad, Appleman, Leonard J., Parikh, Rahul, Mountz, James M.

Journal:

International Journal of Molecular Imaging

Année:

2016

Langue:

english

Fichier:

PDF, 2.64 MB

english, 2016

40

Rate and Determinants of Completing Neoadjuvant Chemotherapy in Medicare Beneficiaries with Bladder Cancer: A SEER-Medicare Analysis

Hugar, Lee A, Yabes, Jonathan G, Turner, Robert M, Fam, Mina M, Appleman, Leonard J, Davies, Benjamin J, Jacobs, Bruce L

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 672 KB

english, 2018

41

Sarcomatoid Renal Cell Carcinoma: A Population-Based Study of 879 Patients

Alevizakos, Michail, Gaitanidis, Apostolos, Nasioudis, Dimitrios, Msaouel, Pavlos, Appleman, Leonard J.

Journal:

Clinical Genitourinary Cancer

Année:

2019

Langue:

english

Fichier:

PDF, 707 KB

english, 2019

42

Cabozantinib, a New Standard of Care for Patients With Advanced Renal Cell Carcinoma and Bone Metastases? Subgroup Analysis of the METEOR Trial

Escudier, Bernard, Powles, Thomas, Motzer, Robert J., Olencki, Thomas, Arén Frontera, Osvaldo, Oudard, Stephane, Rolland, Frederic, Tomczak, Piotr, Castellano, Daniel, Appleman, Leonard J., Drabkin, H

Journal:

Journal of Clinical Oncology

Année:

2018

Fichier:

PDF, 803 KB

2018

43

Cabozantinib, a New Standard of Care for Patients With Advanced Renal Cell Carcinoma and Bone Metastases? Subgroup Analysis of the METEOR Trial

Escudier, Bernard, Powles, Thomas, Motzer, Robert J., Olencki, Thomas, Arén Frontera, Osvaldo, Oudard, Stephane, Rolland, Frederic, Tomczak, Piotr, Castellano, Daniel, Appleman, Leonard J., Drabkin, H

Journal:

Journal of Clinical Oncology

Année:

2018

Langue:

english

Fichier:

PDF, 803 KB

english, 2018

44

Metastasectomy in Advanced Renal Cell Carcinoma: A Systematic Review

Achkar, Tala, Maranchie, Jodi K., Appleman, Leonard J.

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 82 KB

english, 2019

45

Phase I trial of belinostat in combination with 13-cis-retinoic acid in advanced solid tumor malignancies: a California Cancer Consortium NCI/CTEP sponsored trial

Luu, Thehang, Frankel, Paul, Beumer, Jan H., Lim, Dean, Cristea, Mihaela, Appleman, Leonard J., Lenz, Heinz J., Gandara, David R., Kiesel, Brian F., Piekarz, Richard L., Newman, Edward M.

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 680 KB

english, 2019

46

Phase 1 study of veliparib (ABT-888), a poly (ADP-ribose) polymerase inhibitor, with carboplatin and paclitaxel in advanced solid malignancies

Appleman, Leonard J., Beumer, Jan H., Jiang, Yixing, Lin, Yan, Ding, Fei, Puhalla, Shannon, Swartz, Leigh, Owonikoko, Taofeek K., Donald Harvey, R., Stoller, Ronald, Petro, Daniel P., Tawbi, Hussein A

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2019

47

Phase 1 study of veliparib (ABT-888), a poly (ADP-ribose) polymerase inhibitor, with carboplatin and paclitaxel in advanced solid malignancies

Appleman, Leonard J., Beumer, Jan H., Jiang, Yixing, Lin, Yan, Ding, Fei, Puhalla, Shannon, Swartz, Leigh, Owonikoko, Taofeek K., Donald Harvey, R., Stoller, Ronald, Petro, Daniel P., Tawbi, Hussein A

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2019

Fichier:

PDF, 1.01 MB

2019

48

PSMA ADC monotherapy in patients with progressive metastatic castration‐resistant prostate cancer following abiraterone and/or enzalutamide: Efficacy and safety in open‐label single‐arm phase 2 study

Petrylak, Daniel P., Vogelzang, Nicholas J., Chatta, Kamal, Fleming, Mark T., Smith, David C., Appleman, Leonard J., Hussain, Arif, Modiano, Manuel, Singh, Parminder, Tagawa, Scott T., Gore, Ira, McCl

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 941 KB

english, 2019

49

Inhibiting Autophagy in Renal Cell Cancer and the Associated Tumor Endothelium

Russell, Kira L., Gorgulho, Carolina Mendonça, Allen, Abigail, Vakaki, Marianna, Wang, Yue, Facciabene, Andrea, Lee, Daniel, Roy, Partha, Buchser, William J., Appleman, Leonard J., Maranchie, Jodi, St

Journal:

The Cancer Journal

Année:

2019

Fichier:

PDF, 773 KB

2019

50

Multifactorial, biomarker-based predictive models for immunotherapy response enter the arena

Appleman, Leonard J

Journal:

JNCI Journal of the National Cancer Institute

Année:

2020

Fichier:

PDF, 697 KB

2020